School of Infection & Immunity

Dr David Mark

  • Research Associate (Bacteriology)

Publications

List by: Type | Date

Jump to: 2026 | 2025 | 2024 | 2022 | 2021 | 2020
Number of items: 12.

2026

Addington, E. et al. (2026) Catabolism of serine enantiomers represses enterohemorrhagic Escherichia coli virulence factors via modulation of the nitrogen stress response. Proceedings of the National Academy of Sciences, 123(12), e253291612. (doi: 10.1073/pnas.2532916123) (PMID:41849392)

2025

Serrano, E. et al. (2025) Enterohaemorrhagic Escherichia coli AdhE spirosome length correlates with enzymatic directionality and is perturbed by salicylidene acylhydrazides. Open Biology, 15(6), 250041. (doi: 10.1098/rsob.250041) (PMID:40527451) (PMCID:PMC12173503)

McHugh, Rebecca E. ORCID logoORCID: https://orcid.org/0000-0003-4664-6125, Rooney, Liam M. ORCID logoORCID: https://orcid.org/0000-0002-2237-501X, Mark, David R. ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, Wale, Kabo R., Clapperton, Megan, McConnell, Gail, Hoskisson, Paul A., Douce, Gillian R. ORCID logoORCID: https://orcid.org/0000-0002-6654-7346 and Roe, Andrew J. ORCID logoORCID: https://orcid.org/0000-0003-3698-6134 (2025) Evaluating the protective effects of Aurodox in a murine model of Shiga toxin-producing Escherichia coli. npj Antimicrobials and Resistance, 3(1), 23. (doi: 10.1038/s44259-025-00094-3) (PMID:40169888) (PMCID:PMC11962119)

2024

Mark, David R. ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, O'Boyle, Nicky, Wale, Kabo Ronald, Tucker, Samantha K., McHugh, Rebecca E. ORCID logoORCID: https://orcid.org/0000-0003-4664-6125 and Roe, Andrew J. ORCID logoORCID: https://orcid.org/0000-0003-3698-6134 (2024) Aurodox inhibits type III secretion in multiple Gram-negative pathogens. Open Biology, 14(11), 240240. (doi: 10.1098/rsob.240240) (PMID:39591989) (PMCID:PMC11597412)

Wale, Kabo R., O'Boyle, Nicky, McHugh, Rebecca ORCID logoORCID: https://orcid.org/0000-0003-4664-6125, Serrano, Ester ORCID logoORCID: https://orcid.org/0000-0001-5075-2954, Mark, David ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, Douce, Gillian R. ORCID logoORCID: https://orcid.org/0000-0002-6654-7346, Connolly, James P.R. and Roe, Andrew J. ORCID logoORCID: https://orcid.org/0000-0003-3698-6134 (2024) A master regulator of central carbon metabolism directly activates virulence gene expression in attaching and effacing pathogens. PLoS Pathogens, 20(10), e101245. (doi: 10.1371/journal.ppat.1012451) (PMID:39405360) (PMCID:PMC11508082)

Mark, David ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, Trolan, Mia, Douce, Gillian, Roe, Andrew J. ORCID logoORCID: https://orcid.org/0000-0003-3698-6134 and McHugh, Rebecca E. ORCID logoORCID: https://orcid.org/0000-0003-4664-6125 (2024) The enemy within: how pathogen-free are your commercial specific pathogen-free mice? bioRxiv, (doi: 10.1101/2024.07.05.602177)

Mark, David ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, O’Boyle, Nicky, Wale, Kabo R., Tucker, Samantha K., McHugh, Rebecca E. ORCID logoORCID: https://orcid.org/0000-0003-4664-6125 and Roe, Andrew J. ORCID logoORCID: https://orcid.org/0000-0003-3698-6134 (2024) Aurodox, a polyketide from Streptomyces goldiniensis, inhibits transcription of the type III secretion system of multiple Gram-negative pathogens. bioRxiv, (doi: 10.1101/2024.04.19.589875)

2022

Feeney, M. A. et al. (2022) ActinoBase: tools and protocols for researchers working on Streptomyces and other filamentous actinobacteria. Microbial Genomics, 8(7), 000824. (doi: 10.1099/mgen.0.000824) (PMID:35775972) (PMCID:PMC9455695)

2021

Algora-Gallardo, Lis, Schniete, Jana K., Mark, David R. ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, Hunter, Iain S. and Herron, Paul R. (2021) Bilateral symmetry of linear streptomycete chromosomes. Microbial Genomics, 7(11), 000692. (doi: 10.1099/mgen.0.000692) (PMID:34779763) (PMCID:PMC8743542)

Zin, Noraziah M., Ismail, Aishah, Mark, David R. ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, Westrop, Gareth, Schniete, Jana K. and Herron, Paul R. (2021) Adaptation to endophytic lifestyle through genome reduction by Kitasatospora sp. SUK42. Frontiers in Bioengineering and Biotechnology, 9, 740722. (doi: 10.3389/fbioe.2021.740722) (PMID:34712653) (PMCID:PMC8545861)

Rauscher, R. et al. (2021) Positive epistasis between disease-causing missense mutations and silent polymorphism with effect on mRNA translation velocity. Proceedings of the National Academy of Sciences of the United States of America, 118(4), e201061211. (doi: 10.1073/pnas.2010612118) (PMID:33468668) (PMCID:PMC7848603)

2020

Prudence, Samuel M.M., Addington, Emily ORCID logoORCID: https://orcid.org/0009-0005-0462-5627, Castaño-Espriu, Laia, Mark, David R. ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, Pintor-Escobar, Linamaría, Russell, Alicia H. and McLean, Thomas C. (2020) Advances in actinomycete research: an ActinoBase review of 2019. Microbiology, 166(8), pp. 683-694. (doi: 10.1099/mic.0.000944) (PMID:32558638) (PMCID:PMC7641383)

This list was generated on Sat Apr 4 16:47:46 2026 BST.
Jump to: Articles
Number of items: 12.

Articles

Addington, E. et al. (2026) Catabolism of serine enantiomers represses enterohemorrhagic Escherichia coli virulence factors via modulation of the nitrogen stress response. Proceedings of the National Academy of Sciences, 123(12), e253291612. (doi: 10.1073/pnas.2532916123) (PMID:41849392)

Serrano, E. et al. (2025) Enterohaemorrhagic Escherichia coli AdhE spirosome length correlates with enzymatic directionality and is perturbed by salicylidene acylhydrazides. Open Biology, 15(6), 250041. (doi: 10.1098/rsob.250041) (PMID:40527451) (PMCID:PMC12173503)

McHugh, Rebecca E. ORCID logoORCID: https://orcid.org/0000-0003-4664-6125, Rooney, Liam M. ORCID logoORCID: https://orcid.org/0000-0002-2237-501X, Mark, David R. ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, Wale, Kabo R., Clapperton, Megan, McConnell, Gail, Hoskisson, Paul A., Douce, Gillian R. ORCID logoORCID: https://orcid.org/0000-0002-6654-7346 and Roe, Andrew J. ORCID logoORCID: https://orcid.org/0000-0003-3698-6134 (2025) Evaluating the protective effects of Aurodox in a murine model of Shiga toxin-producing Escherichia coli. npj Antimicrobials and Resistance, 3(1), 23. (doi: 10.1038/s44259-025-00094-3) (PMID:40169888) (PMCID:PMC11962119)

Mark, David R. ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, O'Boyle, Nicky, Wale, Kabo Ronald, Tucker, Samantha K., McHugh, Rebecca E. ORCID logoORCID: https://orcid.org/0000-0003-4664-6125 and Roe, Andrew J. ORCID logoORCID: https://orcid.org/0000-0003-3698-6134 (2024) Aurodox inhibits type III secretion in multiple Gram-negative pathogens. Open Biology, 14(11), 240240. (doi: 10.1098/rsob.240240) (PMID:39591989) (PMCID:PMC11597412)

Wale, Kabo R., O'Boyle, Nicky, McHugh, Rebecca ORCID logoORCID: https://orcid.org/0000-0003-4664-6125, Serrano, Ester ORCID logoORCID: https://orcid.org/0000-0001-5075-2954, Mark, David ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, Douce, Gillian R. ORCID logoORCID: https://orcid.org/0000-0002-6654-7346, Connolly, James P.R. and Roe, Andrew J. ORCID logoORCID: https://orcid.org/0000-0003-3698-6134 (2024) A master regulator of central carbon metabolism directly activates virulence gene expression in attaching and effacing pathogens. PLoS Pathogens, 20(10), e101245. (doi: 10.1371/journal.ppat.1012451) (PMID:39405360) (PMCID:PMC11508082)

Mark, David ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, Trolan, Mia, Douce, Gillian, Roe, Andrew J. ORCID logoORCID: https://orcid.org/0000-0003-3698-6134 and McHugh, Rebecca E. ORCID logoORCID: https://orcid.org/0000-0003-4664-6125 (2024) The enemy within: how pathogen-free are your commercial specific pathogen-free mice? bioRxiv, (doi: 10.1101/2024.07.05.602177)

Mark, David ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, O’Boyle, Nicky, Wale, Kabo R., Tucker, Samantha K., McHugh, Rebecca E. ORCID logoORCID: https://orcid.org/0000-0003-4664-6125 and Roe, Andrew J. ORCID logoORCID: https://orcid.org/0000-0003-3698-6134 (2024) Aurodox, a polyketide from Streptomyces goldiniensis, inhibits transcription of the type III secretion system of multiple Gram-negative pathogens. bioRxiv, (doi: 10.1101/2024.04.19.589875)

Feeney, M. A. et al. (2022) ActinoBase: tools and protocols for researchers working on Streptomyces and other filamentous actinobacteria. Microbial Genomics, 8(7), 000824. (doi: 10.1099/mgen.0.000824) (PMID:35775972) (PMCID:PMC9455695)

Algora-Gallardo, Lis, Schniete, Jana K., Mark, David R. ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, Hunter, Iain S. and Herron, Paul R. (2021) Bilateral symmetry of linear streptomycete chromosomes. Microbial Genomics, 7(11), 000692. (doi: 10.1099/mgen.0.000692) (PMID:34779763) (PMCID:PMC8743542)

Zin, Noraziah M., Ismail, Aishah, Mark, David R. ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, Westrop, Gareth, Schniete, Jana K. and Herron, Paul R. (2021) Adaptation to endophytic lifestyle through genome reduction by Kitasatospora sp. SUK42. Frontiers in Bioengineering and Biotechnology, 9, 740722. (doi: 10.3389/fbioe.2021.740722) (PMID:34712653) (PMCID:PMC8545861)

Rauscher, R. et al. (2021) Positive epistasis between disease-causing missense mutations and silent polymorphism with effect on mRNA translation velocity. Proceedings of the National Academy of Sciences of the United States of America, 118(4), e201061211. (doi: 10.1073/pnas.2010612118) (PMID:33468668) (PMCID:PMC7848603)

Prudence, Samuel M.M., Addington, Emily ORCID logoORCID: https://orcid.org/0009-0005-0462-5627, Castaño-Espriu, Laia, Mark, David R. ORCID logoORCID: https://orcid.org/0000-0002-1688-5224, Pintor-Escobar, Linamaría, Russell, Alicia H. and McLean, Thomas C. (2020) Advances in actinomycete research: an ActinoBase review of 2019. Microbiology, 166(8), pp. 683-694. (doi: 10.1099/mic.0.000944) (PMID:32558638) (PMCID:PMC7641383)

This list was generated on Sat Apr 4 16:47:46 2026 BST.